The best medication for male erectile dysfunction is Tadarise 10mg. Men with erectile dysfunction and premature ejaculation are treated with this medication. Tadalafil is a component in this medication. During sexual activity, this chemical helps men achieve longer, harder, and stronger erections. This medication is administered either 30 minutes or 1 hour prior to sexual activity. This medication takes 36 hours to take effect. Alcohol and fatty meals should not be consumed with this medication since they will slow down its effects.