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The long-acting drug delivery technologies market is projected to grow at a CAGR of 13%, till 2035, claims Roots Analysis

In order to mitigate the complexities associated with achieving a long-acting profile, drug developers have been inclined towards the utilization of long-acting drug delivery technologies and outsourcing certain operations to service providers.London
Roots Analysis has announced the addition of “Long-Acting Drug Delivery Technologies and Services Market, 2023-2035” report to its list of offerings.

The conventional treatment options available for several diseases are known to be associated with several challenges, such as patient non-compliance, non-adherence to medication and multiple dosing regimen. In order to circumvent the abovementioned challenges, the demand for long-acting drugs is increasing. The development and manufacturing of these novel pharmacological modalities require advanced long-acting drug delivery technologies and dedicated expertise available with service providers. It is worth mentioning that 70% of the technologies are compatible with injectables (depot and long-acting injections)


Key Market Insights

Over 110 long-acting drug delivery technologies are available, globally
Majority (28%) of the technologies are based on long-acting implants / devices, followed by those based on micro-encapsulation (24%). In addition, close to 40% of the technologies that are compatible with injectables can extend the dosing regimen up to months.

Over 40 companies claim to offer long-acting drug delivery contract services
Presently, the market is dominated by the presence of small (2-50 employees) and mid-sized (51-200 employees) players, who represent 70% of the contemporary market landscape. Notably, around 35% of the total players engaged in this space offer their services at all scales of operation.

Partnership activity in this domain has increased at a CAGR of ~10%, between 2018 and 2021
Maximum number of partnerships were inked in 2021 and 2022, indicating a recent rise in partnership activity. Majority of the deals were acquisitions (15%), followed by product development and technology licensing agreements (14%, each).

More than 570 articles focused on long-acting drug delivery, have been published in reputed scientific journals, since 2017
Around 85% of the publications were focused on research related to long-acting drug delivery. This is indicative of the extensive research activity being carried out in this domain.

Over 1,200 patents have been filed / published related to long-acting drug delivery, since 2018
Over 45% of these were granted patents, while around 55% were patent applications. Further, majority of the patent assignees were industry players. However, it is worth mentioning that the contribution of non-industry players in the overall patent filing activity has increased considerably (CAGR of 10%), over the past few years.

More than 400 grants were awarded to support ongoing R&D activities in long-acting drug delivery, between 2018 and 2022
Collectively, the capital amount awarded to support R&D in this field was estimated to be worth USD 207.2 million. It is worth noting that 97 grants were awarded in 2021, alone. A significant proportion of grants identified in the report (23%) were awarded under the NIH department of internal medicine, followed by those awarded under the department of biomedical engineering (16%).

Increased access to advanced technologies is anticipated to drive growth in this market at a CAGR of 13%, till 2035
Long-acting drug delivery technologies developed for the delivery of small molecules are likely to capture the highest share (~82%) in the market; this trend is unlikely to change in the foreseen future.

Long-acting drug delivery services market is expected to grow at a CAGR of 11%, till 2035
Based on compatible dosage form, majority of the revenue share (50%) is likely to be associated with injectables. On the other hand, the services market for vaginal dosage forms is expected to grow at a faster pace (CAGR of 11.9%), during the forecasted period.

To request a sample copy / brochure of this report, please visit
https://www.rootsanalysis.com/....reports/long-acting-


Frequently Asked Questions
 What are the major factors driving the long-acting drug delivery technologies and services market?
 How many long-acting drug delivery technologies, compatible with long-acting injectables, are available in the market?
 How many long-acting drug delivery technologies demonstrate extended dosage regimen of at least a year?
 How many long-acting drug delivery technologies demonstrate extended dosage regimen of at least a year?
 How many contract service providers possess technology transfer capabilities related to long-acting drug delivery?
 What are the partnership and collaboration trends in the long-acting drug delivery domain?
 What is the current patent landscape of long-acting drug delivery market?
 Which segment, in terms of strategy, accounts for the largest share in the global long-acting drug delivery technologies market?
 Which geography is expected to witness the highest growth rate in the long-acting drug delivery services market?

The financial opportunity within the gene therapy market has been analyzed across the following segments:
 Principle
 Manipulation of drug release from delivery systems
 Manipulation of in vivo clearance

 Strategy
 Chemical Modification
 Micro-encapsulation
 Long-Acting Hydrogels
 Long-Acting Implants
 Long-Acting Microneedles
 Multivesicular Liposomes
 Nanocrystal Suspensions
 Protein Fusion

 Compatible Dosage Form
 Injectables
 Implantables
 Oral Dosage Forms
 Topical / Transdermal Dosage Forms
 Vaginal Dosage Forms
 Other Dosage Forms

 Type of Molecules Delivered
 Small Molecules
 Biologics
 Other Molecules

 Type of Material Used
 Polymer based
 Non-polymer based

 Key Geographical Regions
 North America
 Europe
 Asia-Pacific
 Middle East and North Africa
The research includes brief profiles of key players (listed below) engaged in offering technologies and services related to long-acting drug delivery; each profile features a brief overview of the company, details related to its technology and service portfolio, recent developments and an informed future outlook.
 Adare Pharma Solutions
 AMW
 Bostal Drug Delivery
 Creative Biolabs
 ForDoz Pharma
 Innocore Pharmaceuticals
 Integral BioSystems
 LATITUDE Pharmaceuticals
 Navin Saxena Research and Technology Centre (NSRT)
 Samyang Biopharm

For additional details, please visit https://www.rootsanalysis.com/....reports/long-acting-

You may also be interested in the following titles:

1. Quantum Computing in Drug Discovery Services Market : - Industry Trends and Global Forecasts, 2023-2035
2. Viral Clearance and Viral Testing Services Market : - Industry Trends and Global Forecasts, 2023-2035



About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

 

www.rootsanalysis.com

Request Sample - Long-Acting Drug Delivery Market | Industry Analysis | Market Size | 2035

Long-acting drug delivery technologies, driven by presence of nearly 100 companies, is anticipated to grow at 13% CAGR

Liposome – A Trending Novel Drug Delivery System

In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material.

Liposomes are small, artificial and lipid-based bilayered spherical vesicles, which are created spontaneously by hydrated phospholipids. Owing to their ability to encapsulate bioactive hydrophilic, amphipathic, and lipophilic molecules, liposomes are extensively used as efficient delivery systems for antigens or drugs. They can protect a drug from being detected by the body’s immune system by imitating biological membranes and providing the drug more time to reach its target destination.

To request a sample copy / brochure of this report, please visit https://www.rootsanalysis.com/....reports/liposome-man

Liposomes offer great therapeutic efficacy and safety. They have several applications in the biomedical field such as delivering drug to the desired site while minimizing drug exposure to normal tissues, increased delivery of potential medications to the cytosol, stabilizing therapeutic compounds, and removing barriers to cellular and tissue absorption.

In addition to the applications, liposomes are gaining popularity across various other fields, including drug delivery, agriculture, cosmetics, and food industry. Due to multiple advantages across diverse application areas, including enhanced biocompatibility, high biodegradability, low toxicity, weak immunogenicity, increased drug solubility, controlled distribution, ability to make surface modifications for targeted, extended, and sustained release, liposomes have been recognized as the most effective delivery system. Currently, there are several liposomal formulations clinically approved for the treatment of various diseases, including cancer, fungal and viral infections, and many are currently in advanced stages of clinical studies. Over the years, several companies involved in the development of liposomes have made significant efforts in conducting clinical trials for evaluating the efficacy of liposome-based therapeutics, for the treatment of various oncological disorders.

Owing to various advantages offered by liposomes, advanced liposome technology is being developed to fully substructure the therapeutic applications of liposomes and extensive research is being conducted to develop methods for liposomal formulation with high level of purity and sensitivity. Further, it is extremely desirable to develop novel manufacturing methods that allow for simple encapsulation of both hydrophobic and hydrophilic molecules without the need of organic solvents, specialized equipment, or complex infrastructures. Additionally, given that liposomes have demonstrated some clinical promise as drug delivery systems, future efforts should focus on enhancing the commercial availability and accessibility of liposome products across the globe, particularly in low- and middle-income countries. applications of liposomes in drug delivery (24%), and protein and peptide delivery (9%), which is indicative of the extensive research activities and clinical trials being conducted to evaluate the therapeutic potential of liposomes.


Despite several advancements, there are various challenges in development of liposomes, for which stakeholders are leveraging the expertise of various contract service providers offering development and manufacturing services. These service providers are actively upgrading their capabilities and infrastructure to accommodate the demand for these vesicles. Driven by the growing research efforts, development of advanced methods for preparation and characterization of liposomes, and efforts of various stakeholders, this segment of industry is likely to witness noteworthy growth in the foreseen future.

For additional details, please visit
https://www.rootsanalysis.com/....reports/liposome-man

You may also be interested in the following titles:

1. Quantum Computing in Drug Discovery Services Market : - Industry Trends and Global Forecasts, 2023-2035
2. Viral Clearance and Viral Testing Services Market : - Industry Trends and Global Forecasts, 2023-2035



About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

 

www.rootsanalysis.com

Request Sample - Liposome Development and Liposome Manufacturing | Industry Analysis | Market Size | 2035

Liposome development and liposome manufacturing market, driven by over 70+ players providing services, is expected to grow rapidly in the coming decade

What are the fine capabilities of Agra Etawah Toll Road Project

Modern Road Makers is a private company incorporated on 15 March, 1994. It is classified as a private limited company and is located in Mumbai City, Maharashtra. Its authorized share capital is INR 31.10 cr and the total paid-up capital is INR 31.09 cr. Modern Road Makers operating revenues range is Over INR 500 cr for the financial year ending on 31 March, 2021. Its EBITDA has decreased by -30.23 % over the previous year. At the same time, its book networth has increased by 6.33 %.

The Agra Etawah Toll Road Project consists of the stretch of NH 2 between kilometers 199.66 and 323.525.

AETPL has been granted permission to feature six lanes to a 124. Fifty two km stretch of Uttar Pradesh's NH 2 on a BOT or DBFOT basis.

A list of the task's capabilities is provided beneath.

six-lane road measuring 124.52 kilometers in length.
84.725 kilometers make up the 750 lane-kilometer Administration road.
Slip road with a length of 30.282 km and three significant additions.
30 minor augmentations.
In the skies, seven.
Turbulence forces seven rail tracks to pass past 3.08 km of obstacles.
The lamps illuminate the 44.68 kilometers of the route.
Located in 164 underpasses, a confluence of 214 vehicular underpasses, 10 for light traffic, and 6 for pedestrians.
Four trucks stop 22 straight lanes of traffic.
Two toll-cost courts are necessary. FASTag
Cost of the project is Rs. 3,244 Cr.
The concession is valid for 24 years.

In This Highway Trip (Agra Etawah Toll Road Project) you will come across different scenic spots on your way to the destination. Various restaurants offer delicious food. while in agra you can witness the uttar pradesh culture and enjoy food form uttar pradesh dhabas. It's one of the most comfortable and smooth driving highways. You will be in a different world and be in awe of the beauty of the road. It is a well-planned road with six-lane concrete, which is India’s first. You can take short breaks on the trip to admire the scenic beauty. On both sides of the road, you will find Dhaba and Hotels. While traveling through this road, you can also make a pit-stop at Bharatpur National Park, the fourth famous vacationer site and Three globally renowned traveler destinations—the Taj Mahal, Fatehpur Sikri, and Red Post—have established Agra as a well-known vacation spot on the tour industry's map.. If you look at the India road trip route map, this is the most scenic highway you can find.

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The 3D printing technology has garnered significant attention from stakeholders in the dental industry

3D printing, also known as additive manufacturing, is a method of producing 3-dimensional objects layer-by-layer, using a computer aided design.Owing to its ability to print complex models using a wide range of materials, 3D printing has applications across various industries, including dental, aerospace, automotive, healthcare, food, fashion, mechanical engineering and other manufacturing industries.

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It is worth mentioning that the number of dental 3D printer manufacturers has gradually increased over the past decades. In recent years, the adoption of 3D printers has risen at a commendable pace, specifically in the dental industry. This is primarily due to the increasing scope of inhouse dental 3D printing, growth in digital dentistry business and rise in the demand for 3D printed products. 3D printing in dental industry is an advanced solution which produces high quality and more accurate dental products (including, crown and bridges, dentures, surgical guides and dental implants). Moreover, the process of dental 3D printing is time saving and economical for both the patients and dentists. Driven by the growing prevalence of dental diseases and rising demand for high quality dental products, the dental 3D printing market is anticipated to witness a steady growth in the foreseen future. During our research, we identified 80 dental 3D printers companies offered close to 230 dental 3D printers across the globe.

For additional details, please visit
https://www.rootsanalysis.com/....reports/dental-3d-pr or email sales@rootsanalysis.com

You may also be interested in the following titles:
1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035
2. 4D Bioprinting Market : Industry Trends and Global Forecasts, 2022-2035


About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

Genotoxicity / Mutagenicity Testing

Genotoxicity refers to the property of physical, chemical, and biological agents to cause damage to genetic information present within a cell. It is worth mentioning that this damage can lead to formation of mutations, activation of mistimed event and direct DNA damage.

Further, researchers have been able to link the mutations caused by genetic toxicology to various disease indications, including several oncological and genetic disorders. In addition, it is believed that the changes introduced in the genetic material can be passed down to future cell generations. Similarly, mutagenicity refers to the introduction of perpetual transmissible changes in the genomic structure of organisms, enabling mutations in cells. Therefore, testing of genotoxicity / mutagenicity is an essential component of the safety assessment of products, with the objective of preventing certain particles from negatively impacting the human health.

To request a sample copy / brochure of this report, please visit this
https://www.rootsanalysis.com/....reports/genotoxicity

Testing techniques used for genotoxicity / mutagenicity testing:

 Ames test: It is used to evaluate an agent’s mutagenic potential by reversing mutations in the tester mutant bacteria (E. coli, Salmonella typhi), as well as its ability to synthesize an essential amino acid required for growth.

 Mouse Lymphoma Assay / Hypoxanthine Guanine Phosphoribosyl Transferase: Mouse Lymphoma Assay is employed to assess an agent’s genotoxic potential. It determines the genetic variations affecting the expression of the thymidine kinase gene located on chromosome.

 Mutation Assay: Transgenic rodent somatic and germ cell gene mutation assay specifies an in vivo assay that perceives gene mutation causing agents. Transgenic mice or rats with several copies of chromosomally integrated plasmids or phage shuttle vectors are employed in this test.
 Comet Assay: The comet assay, also known as single cell gel electrophoresis (SCGE), is an efficient technique for identifying DNA strand breaks in a cell. It is used in molecular epidemiology, genotoxicity testing, and basic studies on DNA damage and repair.
 Chromosomal Aberration Test: The test is used to evaluate a substance's possible genotoxic risk. Mammalian cells are cultivated in vitro, exposed to a test substance, extracted, and then the frequency of structural asymmetry of the chromosomes is determined.
 Micronucleus Test: The micronucleus identifies chemicals (liquid or solid) that lead to cytogenetic damage, resulting in the formation of micronuclei containing complete or lagging chromosomal segments.

Hence, it can be concluded that players offering services for genotoxicity / mutagenicity testing have now become an integral part of various industries. Furthermore, considering the various active initiatives being undertaken by players based in this domain, we are led to believe that the opportunity for stakeholders in this industry is likely to grow at an exponential pace in the foreseen future.

For additional details, please visit
https://www.rootsanalysis.com/....reports/genotoxicity or email sales@rootsanalysis.com

You may also be interested in the following titles:
1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035
2. 4D Bioprinting Market : Industry Trends and Global Forecasts, 2022-2035


About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com